In 2020, the Centers for Medicare & Medicaid Services issued the Interoperability and Patient Access Final Rule that requires CMS-regulated payers to implement and maintain a secure, standards-based patient access application program interface (API) using the FHIR standard. This includes programs such as Medicare advantage, state Medicaid programs, and other qualified health plans through the Federally Facilitated Marketplace. These organizations, including state and regional health information exchanges (HIEs), have until July 1, 2021, to meet this standard.